Lot numbers can be found on the outside label of a product:
DMT-OMe-rC(Ac)
-
CAS No. 199593-08-3
- Cat. No. CS-0172019
- Purity≥97%
- MDL No.MFCD08704192
*For research and further manufacturing use only, not for direct human use.
Structure of 199593-08-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 199593-08-3
- Cat. No. CS-0172019
- Purity ≥97%
- MDL No. MFCD08704192
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₃₃H₃₅N₃O₈
- Molecular Weight 601.65
- Synonym(s) N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
- SMILES O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@@H]1COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
Description
DMT-OMe-rC(Ac) is a protected ribocytidine derivative featuring a dimethoxytrityl (DMT) group at the 5′-OH and an acetyl moiety on the N4-amino function. This configuration enables orthogonal protection during oligonucleotide synthesis, offering enhanced stability and controlled deprotection sequences for efficient incorporation into RNA strands.
Application
DMT-OMe-rC(Ac) serves as a versatile phosphoramidite building block for solid-phase oligonucleotide synthesis, enabling the incorporation of acetylated 2'-deoxyribofuranosyl cytidine residues with high fidelity. The dimethoxytrityl (DMT) group provides robust protection and convenient monitoring via UV detection, while the OMe and Ac modifications enhance nucleoside stability and modulate hybridization properties. This derivative facilitates efficient coupling and selective deprotection, supporting reliable synthesis of modified DNA strands for research and diagnostic applications.
Synthesis
-
References
-
Reddy; Hanna, Naeem B.; Farooqui, Firdous Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1589 - 1598
-
-
Route2
-
In-stock
85335-73-5 - ~%
-
In-stock
199593-08-3
References
-
Reddy; Hanna, Naeem B.; Farooqui, Firdous Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1589 - 1598
-
-
Route3
-
In-stock
3768-18-1 - ~%
-
In-stock
199593-08-3
References
-
Reddy; Hanna, Naeem B.; Farooqui, Firdous Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1589 - 1598
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H320-H335
|
|
|
Precautionary Statements : P261-P280-P302+P352
|
|
Quality Control
Computational Chemistry Data
- TPSA 130.37
- LogP 3.5009
- H_Acceptors 10
- H_Donors 2
- Rotatable_Bonds 11
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- DMT-OMe-rC(Ac) sigmaDMT-OMe-rC(Ac) manufacturerDMT-OMe-rC(Ac) priceDMT-OMe-rC(Ac) structureDMT-OMe-rC(Ac) SDSbuy DMT-OMe-rC(Ac)DMT-OMe-rC(Ac) supplierDMT-OMe-rC(Ac) usesDMT-OMe-rC(Ac) molecular weightprice of DMT-OMe-rC(Ac)DMT-OMe-rC(Ac) chemical name formula of DMT-OMe-rC(Ac)