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tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate

  • CAS No. 199336-83-9

  • Cat. No. CS-0048580
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate|CS-0048580

Structure of 199336-83-9

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General Information

  • CAS No. 199336-83-9
  • Cat. No. CS-0048580
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₂
  • Molecular Weight 200.28
  • Synonym(s) (R)-tert-butyl 3-(methylamino)pyrrolidine-1-carboxylate
  • SMILES CN[C@@H]1CCN(C1)C(=O)OC(C)(C)C

Description

tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate is a stereochemically defined, bench-stable chiral building block featuring a pyrrolidine core with a methylamino substituent at the 3-position. This configuration supports efficient incorporation into bioactive molecule synthesis, particularly in medicinal chemistry and peptide analog development.

Application

tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate serves as a stereochemically defined, bench-stable building block for the synthesis of bioactive nitrogen-containing heterocycles. The protected amine and pyrrolidine core enable straightforward functionalization via standard deprotection and coupling protocols, supporting diverse transformations in medicinal chemistry and process development. Its compatibility with common reaction conditions facilitates efficient access to chiral pharmacophores.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.2152
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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