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CS-W001157 4
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Methyl pyrrolidine-3-carboxylate hydrochloride

  • CAS No. 198959-37-4

  • Cat. No. CS-W001842
  • Purity≥95%
  • MDL No.MFCD08436169

*For research and further manufacturing use only, not for direct human use.

Methyl pyrrolidine-3-carboxylate hydrochloride|CS-W001842

Structure of 198959-37-4

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General Information

  • CAS No. 198959-37-4
  • Cat. No. CS-W001842
  • Purity ≥95%
  • MDL No. MFCD08436169
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₂
  • Molecular Weight 165.62
  • Synonym(s) 1-Methylpyrrolidine-3-carboxylate hydrochloride
  • SMILES COC(=O)C1CNCC1.Cl

Description

Methyl pyrrolidine-3-carboxylate hydrochloride is a bench-stable, moisture-tolerant building block featuring a tertiary amine moiety flanked by a carbonyl and methyl ester group. This zwitterionic character enhances solubility in polar solvents while enabling straightforward derivatization in synthetic organic chemistry and peptide-like scaffold development.

Application

Methyl pyrrolidine-3-carboxylate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrrolidine-containing scaffolds via standard functional group manipulations. The protonated amine enhances solubility and stability in polar media, while the ester group supports diverse transformations including reduction, hydrolysis, and coupling reactions. Its bench-stable crystalline form facilitates handling and purification in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.1907
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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