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CS-W001157 4
Total: USD 88.00

1-Azaspiro[3.3]heptane hydrochloride

  • CAS No. 1986337-29-4

  • Cat. No. CS-0131307
  • Purity≥95%
  • MDL No.MFCD26406838

*For research and further manufacturing use only, not for direct human use.

1-Azaspiro[3.3]heptane hydrochloride|CS-0131307

Structure of 1986337-29-4

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General Information

  • CAS No. 1986337-29-4
  • Cat. No. CS-0131307
  • Purity ≥95%
  • MDL No. MFCD26406838
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClN
  • Molecular Weight 133.62
  • Synonym(s) 1-Azaspiro[3.3]heptane hcl
  • SMILES [H]Cl.N1CCC12CCC2

Description

1-Azaspiro[3.3]heptane hydrochloride is a rigid, nitrogen-containing spirocyclic scaffold offering enhanced metabolic stability and favorable conformational control. This bench-stable salt form improves solubility and handling in synthetic workflows, enabling efficient integration into medicinal chemistry campaigns targeting constrained bioactive architectures.

Application

1-Azaspiro[3.3]heptane hydrochloride serves as a rigid, conformationally constrained heterocyclic scaffold widely employed in medicinal chemistry for probing bioactive molecular architectures. Its spirocyclic structure imparts high metabolic stability and defined 3D orientation, enabling efficient exploration of stereochemical space in target-directed synthesis. The hydrochloride salt enhances solubility and handling, facilitating use in standard coupling reactions and functional group interconversions. This compound functions as a versatile building block in the construction of complex nitrogen-containing ring systems relevant to pharmaceutical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.3242
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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