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CS-W001157 4
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Ethyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride

  • CAS No. 1983157-41-0

  • Cat. No. CS-0148013
  • Molecule weight219.71
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride|CS-0148013

Structure of 1983157-41-0

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General Information

  • CAS No. 1983157-41-0
  • Cat. No. CS-0148013
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈ClNO₂
  • Molecular Weight 219.71
  • Synonym(s) None
  • SMILES O=C(C1CC12CCNCC2)OCC.[H]Cl

Description

Ethyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride delivers a rigid, nitrogen-containing spirocyclic scaffold ideal for medicinal chemistry libraries. This bench-stable derivative features enhanced solubility and predictable reactivity, enabling efficient incorporation into target-oriented synthesis campaigns.

Application

Ethyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride serves as a versatile spirocyclic building block in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles. Its stable crystalline form and solubility profile facilitate handling and purification. The protected amine functionality tolerates a range of reaction conditions, supporting diverse transformations including reductive amination, coupling reactions, and functional group interconversions. This scaffold is well-documented in synthetic routes to bioactive compounds and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.361
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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