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(E)-4-(Piperidin-1-yl)but-2-enoic acid hydrochloride

  • CAS No. 197892-69-6

  • Cat. No. CS-0120306
  • Purity≥95%
  • MDL No.MFCD14636476

*For research and further manufacturing use only, not for direct human use.

(E)-4-(Piperidin-1-yl)but-2-enoic acid hydrochloride|CS-0120306

Structure of 197892-69-6

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General Information

  • CAS No. 197892-69-6
  • Cat. No. CS-0120306
  • Purity ≥95%
  • MDL No. MFCD14636476
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆ClNO₂
  • Molecular Weight 205.68
  • Synonym(s) (2E)-4-(piperidin-1-yl)but-2-enoic acid hydrochloride
  • SMILES OC(/C=C/CN1CCCCC1)=O.Cl[H]

Description

This (E)-configured piperidinylbutenoic acid hydrochloride features a conjugated enoic acid system paired with a basic piperidine moiety, enabling efficient integration into bioactive molecule scaffolds. The salt form enhances solubility and handling under standard conditions, supporting use in synthetic medicinal chemistry workflows.

Application

(E)-4-(Piperidin-1-yl)but-2-enoic acid hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutically relevant scaffolds. The conjugated enoic acid functionality enables efficient Michael additions and Diels–Alder reactions, while the piperidine moiety provides a basic nitrogen for derivatization. Its hydrochloride salt form enhances bench stability and solubility in polar solvents, facilitating purification and integration into multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   2.171
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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