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CS-W001157 4
Total: USD 88.00

N-Me-Asp(Otbu)-OH

  • CAS No. 197632-85-2

  • Cat. No. CS-0196954
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-Me-Asp(Otbu)-OH|CS-0196954

Structure of 197632-85-2

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Description

N-Me-Asp(Otbu)-OH is a sterically hindered, bench-stable amino acid derivative featuring a tert-butyl ester and N-methylated backbone. This configuration enhances resistance to racemization during coupling, enabling reliable incorporation into peptide sequences under standard conditions. The protected side chain facilitates efficient synthesis of complex peptides without interference from carboxylic acid reactivity.

Application

N-Me-Asp(Otbu)-OH serves as a valuable building block in peptide synthesis, offering a stable, bench-ready source of N-methylaspartic acid with orthogonal protection. The OtBu group enables selective deprotection under mild acidic conditions, while the N-methyl substitution enhances metabolic stability and conformational rigidity in bioactive peptides. Its compatibility with standard coupling protocols and resistance to racemization facilitates efficient incorporation into complex sequences.

General Information

  • CAS No. 197632-85-2
  • Cat. No. CS-0196954
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₄
  • Molecular Weight 203.24
  • Synonym(s) None
  • SMILES CC(C)(C)OC(=O)C[C@@H](C(=O)O)NC

Computational Chemistry Data

  • TPSA   75.63
  • LogP   0.3908
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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