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CS-W001157 4
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S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine

  • CAS No. 19746-37-3

  • Cat. No. CS-W004153
  • Purity≥96%
  • MDL No.MFCD00038252

*For research and further manufacturing use only, not for direct human use.

S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine|CS-W004153

Structure of 19746-37-3

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General Information

  • CAS No. 19746-37-3
  • Cat. No. CS-W004153
  • Purity ≥96%
  • MDL No. MFCD00038252
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀N₂O₅S
  • Molecular Weight 292.35
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CSCNC(C)=O)NC(OC(C)(C)C)=O

Description

S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine features a protected thiol group and an N-terminal Boc moiety, enabling stable incorporation into peptide sequences. The acetamidomethyl side chain provides a masked sulfhydryl for controlled conjugation, while the tert-butoxycarbonyl group ensures compatibility with standard Fmoc solid-phase synthesis protocols.

Synthesis

  • Route1
    • null|null
      1070-19-5
    • S-(Acetamidomethyl)-L-cysteine hydrochloride|CS-W010398
      28798-28-9
    • ~%
    • In-stock
      S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine|CS-W004153
      19746-37-3

    References

    • Journal of the American Chemical Society, , vol. 94, # 15 p. 5456 - 5461
  • Route2
    • null|null
      1070-19-5
    • H-Cys(Acm)-OH|CS-0636612
      19647-70-2
    • ~%
    • In-stock
      S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine|CS-W004153
      19746-37-3

    References

    • Tetrahedron letters, , vol. 26, p. 3057 - 3058
  • Route3
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • S-(Acetamidomethyl)-L-cysteine hydrochloride|CS-W010398
      28798-28-9
    • ~%
    • In-stock
      S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine|CS-W004153
      19746-37-3

    References

    • Chemistry of Natural Compounds, , vol. 15, p. 471 - 476 Khimiya Prirodnykh Soedinenii, , vol. 15, p. 543 - 548

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   104.73
  • LogP   0.7911
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   6

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