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CS-W001157 4
Total: USD 88.00

N6-Propionyl-L-lysine

  • CAS No. 1974-17-0

  • Cat. No. CS-0100604
  • Purity≥97%
  • MDL No.MFCD26793597

*For research and further manufacturing use only, not for direct human use.

N6-Propionyl-L-lysine|CS-0100604

Structure of 1974-17-0

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General Information

  • CAS No. 1974-17-0
  • Cat. No. CS-0100604
  • Purity ≥97%
  • MDL No. MFCD26793597
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O₃
  • Molecular Weight 202.25
  • Synonym(s) None
  • SMILES N[C@@H](CCCCNC(CC)=O)C(O)=O

Description

N6-Propionyl-L-lysine delivers a stable, moisture-tolerant acyl modification at the ε-amino group of lysine, enabling direct incorporation into peptide synthesis workflows. This derivative features enhanced solubility and compatibility with standard coupling protocols, streamlining access to site-specifically modified peptides for biochemical studies.

Application

N6-Propionyl-L-lysine serves as a stable, bench-ready amino acid building block for the synthesis of peptide-based epigenetic probes and modified histone mimetics. The propionyl group at the ε-amino position provides enhanced metabolic stability and facilitates orthogonal deprotection strategies in solid-phase synthesis. Its well-defined reactivity enables reliable incorporation into complex peptides without side-chain interference, making it a practical choice for medicinal chemistry and biochemical assay development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   92.42
  • LogP   0.0948
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   7

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