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CS-W001157 4
Total: USD 88.00

Glycyl-L-valine

  • CAS No. 1963-21-9

  • Cat. No. CS-W017501
  • Purity≥97%
  • MDL No.MFCD00066046

*For research and further manufacturing use only, not for direct human use.

Glycyl-L-valine|CS-W017501

Structure of 1963-21-9

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General Information

  • CAS No. 1963-21-9
  • Cat. No. CS-W017501
  • Purity ≥97%
  • MDL No. MFCD00066046
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄N₂O₃
  • Molecular Weight 174.20
  • Synonym(s) None
  • SMILES CC(C)[C@H](NC(CN)=O)C(O)=O

Description

Glycyl-L-valine is a dipeptide featuring a glycine residue linked to L-valine via a stable amide bond. This sequence offers enhanced solubility and metabolic stability compared to simpler amino acid derivatives, making it suitable for peptide synthesis intermediates and bioactive molecule scaffolds in medicinal chemistry research.

Application

Glycyl-L-valine serves as a reliable dipeptide building block for peptide synthesis, offering enhanced stability and solubility in aqueous and organic media. Its well-defined stereochemistry and compatibility with standard coupling protocols facilitate efficient amide bond formation, while the protected α-amino and carboxyl groups enable straightforward incorporation into larger peptide sequences. Functions effectively in solid-phase and solution-phase workflows, supporting scalable production of bioactive peptides and peptidomimetics.

Synthesis

  • Route1
    • N-Chloroacetyl-DL-valine|CS-0201912
      4090-17-9
    • ~%
    • In-stock
      Glycyl-L-valine|CS-W017501
      1963-21-9

    References

    • Justus Liebigs Annalen der Chemie, , vol. 363, p. 158,159 Chemische Berichte, , vol. 41, p. 890,2892, 2898
  • Route2
    • null|null
      23937-14-6
    • ~%
    • In-stock
      Glycyl-L-valine|CS-W017501
      1963-21-9

    References

    • Journal of the Chemical Society [Section] C: Organic, , p. 1911 - 1916
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 37, p. 327 - 329

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   92.42
  • LogP   -0.8295
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   4

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