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Methyl 2-(piperazin-1-yl)acetate hydrochloride

  • CAS No. 196192-08-2

  • Cat. No. CS-0150680
  • Molecule weight194.66
  • Purity≥95%
  • MDL No.MFCD09054704

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(piperazin-1-yl)acetate hydrochloride|CS-0150680

Structure of 196192-08-2

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General Information

  • CAS No. 196192-08-2
  • Cat. No. CS-0150680
  • Purity ≥95%
  • MDL No. MFCD09054704
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅ClN₂O₂
  • Molecular Weight 194.66
  • Synonym(s) N-Methoxycarbonylmethylpiperazine hydrochloride
  • SMILES COC(=O)CN1CCNCC1.Cl

Description

Methyl 2-(piperazin-1-yl)acetate hydrochloride features a piperazine ring tethered to an ester-functionalized acetyl linker, delivering enhanced solubility and stability under standard conditions. This bench-stable salt form facilitates efficient incorporation into medicinal chemistry libraries, serving as a key scaffold for bioactive molecule design.

Application

Methyl 2-(piperazin-1-yl)acetate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to piperazine-containing scaffolds. Its bench-stable nature and compatibility with standard coupling reactions facilitate rapid diversification of drug candidates. The molecule functions as a key intermediate in the synthesis of bioactive heterocycles and functionalized amine derivatives, offering excellent solubility and ease of purification in routine synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   -0.5136
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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