Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,3-Bis(4-(trifluoromethyl)phenyl)urea

  • CAS No. 1960-88-9

  • Cat. No. CS-0182192
  • Purity≥98%
  • MDL No.MFCD01908917

*For research and further manufacturing use only, not for direct human use.

1,3-Bis(4-(trifluoromethyl)phenyl)urea|CS-0182192

Structure of 1960-88-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1960-88-9
  • Cat. No. CS-0182192
  • Purity ≥98%
  • MDL No. MFCD01908917
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₀F₆N₂O
  • Molecular Weight 348.24
  • Synonym(s) 1,3-Bis[4-(trifluoromethyl)phenyl]urea
  • SMILES O=C(NC1=CC=C(C(F)(F)F)C=C1)NC2=CC=C(C(F)(F)F)C=C2

Description

1,3-Bis(4-(trifluoromethyl)phenyl)urea features a rigid, electron-deficient core flanked by two trifluoromethyl-substituted aryl groups, enhancing stability and solubility in polar aprotic solvents. This structure enables robust participation in hydrogen-bonding networks, making it valuable for supramolecular assembly and crystal engineering applications.

Application

1,3-Bis(4-(trifluoromethyl)phenyl)urea serves as a robust scaffold in medicinal chemistry, offering enhanced metabolic stability and lipophilicity due to its perfluorinated aryl substituents. The urea linkage enables hydrogen bonding interactions in target binding, while the sterically hindered structure imparts excellent bench stability and compatibility with diverse reaction conditions. It functions effectively as a building block for bioactive heterocycles and protein-binding motifs in lead optimization campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.13
  • LogP   5.3682
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,3-Bis(4-(trifluoromethyl)phenyl)urea sigma1,3-Bis(4-(trifluoromethyl)phenyl)urea manufacturer1,3-Bis(4-(trifluoromethyl)phenyl)urea price1,3-Bis(4-(trifluoromethyl)phenyl)urea structure1,3-Bis(4-(trifluoromethyl)phenyl)urea SDSbuy 1,3-Bis(4-(trifluoromethyl)phenyl)urea1,3-Bis(4-(trifluoromethyl)phenyl)urea supplier1,3-Bis(4-(trifluoromethyl)phenyl)urea uses1,3-Bis(4-(trifluoromethyl)phenyl)urea molecular weightprice of 1,3-Bis(4-(trifluoromethyl)phenyl)urea1,3-Bis(4-(trifluoromethyl)phenyl)urea chemical name formula of 1,3-Bis(4-(trifluoromethyl)phenyl)urea
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label