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Structure of 19578-68-8
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1-(Benzyloxy)-4-iodobenzene features a para-iodinated aromatic ring coupled to a benzyloxy substituent, enabling seamless incorporation into cross-coupling reactions. The electron-deficient iodide facilitates efficient palladium-catalyzed transformations, while the benzyloxy group offers stability and orthogonal reactivity. This compound serves as a key building block in the synthesis of functionalized biaryls and advanced pharmaceutical intermediates.
1-(Benzyloxy)-4-iodobenzene serves as a versatile aryl iodide building block for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The benzyloxy group provides excellent stability and mild deprotection compatibility, facilitating sequential functionalization in complex molecule synthesis. Its bench-stable nature and predictable reactivity make it ideal for iterative synthetic strategies in medicinal chemistry and materials science.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: