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Structure of 142523-69-1
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1-(Benzyloxy)-2-iodobenzene features a benzyl ether-linked aryl iodide scaffold, enabling efficient cross-coupling reactions under palladium catalysis. The benzyloxy group enhances solubility and stability, while the ortho-iodo substitution facilitates regioselective transformations. This reagent streamlines access to complex biaryl architectures in medicinal chemistry and materials synthesis.
1-(Benzyloxy)-2-iodobenzene serves as a versatile aryl iodide building block in transition-metal-catalyzed cross-coupling reactions. The benzyloxy group provides orthogonal stability and selective deprotection options, while the iodine moiety enables efficient Suzuki, Stille, and Negishi couplings. This compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: