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CS-W001157 4
Total: USD 88.00

(S)-7-Methylchroman-4-amine hydrochloride

  • CAS No. 1956436-49-9

  • Cat. No. CS-0162023
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-7-Methylchroman-4-amine hydrochloride|CS-0162023

Structure of 1956436-49-9

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General Information

  • CAS No. 1956436-49-9
  • Cat. No. CS-0162023
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄ClNO
  • Molecular Weight 199.68
  • Synonym(s) (4S)-7-METHYL-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-AMINE HCl
  • SMILES N[C@H]1CCOC2=C1C=CC(C)=C2.[H]Cl

Description

(S)-7-Methylchroman-4-amine hydrochloride is a chiral amine scaffold featuring a fused chroman ring system with a methyl group at the 7-position and a primary amine at the 4-position. This bench-stable salt exhibits enhanced solubility in aqueous and polar organic media, enabling efficient incorporation into medicinal chemistry campaigns. The stereochemistry at the chiral center supports selective interactions in biological target engagement, making it a valuable building block for CNS-targeted drug discovery programs.

Application

(S)-7-Methylchroman-4-amine hydrochloride serves as a versatile chiral building block for medicinal chemistry, enabling efficient access to substituted chroman scaffolds prevalent in bioactive molecules. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination, while the hydrochloride salt ensures excellent bench stability and ease of handling. The stereochemistry at the 4-position is well-defined, supporting enantioselective synthesis in target-oriented campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.19912
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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