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Structure of 195457-71-7
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4'-Trifluoromethylbiphenyl-4-carboxylic acid features a biphenyl scaffold bearing a trifluoromethyl group at the para position of one phenyl ring and a carboxylic acid at the opposite end. This electron-deficient aryl moiety integrates readily into cross-coupling reactions and serves as a key building block in pharmaceutical and materials chemistry.
4'-Trifluoromethylbiphenyl-4-carboxylic acid serves as a valuable building block in the synthesis of functionalized biaryl scaffolds, offering enhanced metabolic stability and lipophilicity due to the trifluoromethyl group. Its carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation, facilitating integration into pharmaceutical intermediates and materials chemistry applications. The compound exhibits good bench stability and is compatible with standard coupling reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: