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CS-W001157 4
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(4S,4'S)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)

  • CAS No. 195379-09-0

  • Cat. No. CS-0103901
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4S,4'S)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)|CS-0103901

Structure of 195379-09-0

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General Information

  • CAS No. 195379-09-0
  • Cat. No. CS-0103901
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈N₂O₂
  • Molecular Weight 292.42
  • Synonym(s) None
  • SMILES CC(C)(C)[C@@H]1N=C(C2(C3=N[C@@H](C(C)(C)C)CO3)CC2)OC1

Description

This cyclopropane-bridged bisoxazole features a rigid, chiral scaffold with two tert-butyl-substituted dihydrooxazole rings. The steric bulk of the tert-butyl groups enhances stability and solubility, while the cyclopropane linkage enforces conformational rigidity. Ideal for asymmetric synthesis and molecular scaffold design in medicinal chemistry.

Application

(4S,4'S)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) serves as a chiral, bench-stable scaffold for asymmetric synthesis, enabling the construction of complex heterocyclic architectures via controlled C–C and C–X bond formation. Its rigid cyclopropane core imparts conformational constraint, while the tert-butyl-substituted dihydrooxazoles offer excellent functional group tolerance and ease of purification, making it valuable in medicinal chemistry and catalyst design workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   3.4534
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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