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3-(Thiophen-2-yl)propan-1-ol

  • CAS No. 19498-72-7

  • Cat. No. CS-0158400
  • Molecule weight142.22
  • Purity≥95%
  • MDL No.MFCD09927267

*For research and further manufacturing use only, not for direct human use.

3-(Thiophen-2-yl)propan-1-ol|CS-0158400

Structure of 19498-72-7

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General Information

  • CAS No. 19498-72-7
  • Cat. No. CS-0158400
  • Purity ≥95%
  • MDL No. MFCD09927267
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀OS
  • Molecular Weight 142.22
  • Synonym(s) 3-(2-Thienyl)propan-1-ol
  • SMILES C(CC1=CC=CS1)CO

Description

3-(Thiophen-2-yl)propan-1-ol features a thiophene ring linked via a propylene spacer to a primary alcohol, delivering a rigid, electron-rich scaffold. This combination enables direct incorporation into conjugated systems and facilitates functionalization in synthetic routes requiring polar handles. The molecule exhibits favorable solubility in common organic solvents and maintains stability under standard bench conditions.

Application

3-(Thiophen-2-yl)propan-1-ol serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of bioactive heterocycles and pharmaceutical intermediates. Its thiophene moiety offers enhanced metabolic stability and π-stacking potential, while the primary alcohol facilitates straightforward derivatization via esterification, etherification, or oxidation to aldehyde. Bench-stable and compatible with standard reaction conditions, it functions reliably in coupling processes and multistep syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.673
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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