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CS-W001157 4
Total: USD 88.00

2-Bromo-1,3-dichlorobenzene

  • CAS No. 19393-92-1

  • Cat. No. CS-W013036
  • Purity≥98%
  • MDL No.MFCD00000574

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1,3-dichlorobenzene|CS-W013036

Structure of 19393-92-1

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General Information

  • CAS No. 19393-92-1
  • Cat. No. CS-W013036
  • Purity ≥98%
  • MDL No. MFCD00000574
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrCl₂
  • Molecular Weight 225.89
  • Synonym(s) 2,6-DICHLOROPHENYL BROMIDE
  • SMILES ClC1=C(Br)C(Cl)=CC=C1

Description

2-Bromo-1,3-dichlorobenzene is a halogenated aromatic compound featuring bromine and two chlorine atoms at meta positions relative to each other. This electron-deficient scaffold serves as a robust building block in cross-coupling reactions, particularly in the synthesis of complex pharmaceutical intermediates and functional materials.

Application

2-Bromo-1,3-dichlorobenzene serves as a versatile building block in cross-coupling chemistry, enabling palladium-catalyzed reactions such as Suzuki-Miyaura and Stille couplings. Its ortho-halogenated structure provides predictable regioselectivity, while the stability of the dichloro substituents supports robust handling and purification. Functions effectively in the synthesis of biaryl scaffolds and heterocyclic intermediates relevant to medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      401631-85-4
    • ~67%
    • In-stock
      2-Bromo-1,3-dichlorobenzene|CS-W013036
      19393-92-1
    • null|null
      541-73-1

    References

    • Synthesis, , # 14 p. 2180 - 2190
  • Route2

    References

    • Journal of the Chemical Society, , vol. 79, p. 1303
  • Route3
    • 3-Bromo-2,4-dichloroaniline|CS-0197744
      80026-10-4
    • ~%
    • In-stock
      2-Bromo-1,3-dichlorobenzene|CS-W013036
      19393-92-1

    References

    • Journal of the Chemical Society, , vol. 79, p. 1303

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.7559
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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