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CS-W001157 4
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tert-Butyl (3-bromocyclobutyl)carbamate

  • CAS No. 1936399-47-1

  • Cat. No. CS-0312181
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3-bromocyclobutyl)carbamate|CS-0312181

Structure of 1936399-47-1

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General Information

  • CAS No. 1936399-47-1
  • Cat. No. CS-0312181
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆BrNO₂
  • Molecular Weight 250.13
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC1CC(Br)C1

Description

tert-Butyl (3-bromocyclobutyl)carbamate features a brominated cyclobutyl ring tethered to a bench-stable tert-butyl carbamate group, enabling direct incorporation into synthetic sequences. The pendant bromine facilitates palladium-catalyzed cross-coupling reactions, while the protecting group remains intact under standard reaction conditions. This combination supports efficient access to functionalized cyclic scaffolds in medicinal chemistry and process development workflows.

Application

tert-Butyl (3-bromocyclobutyl)carbamate serves as a versatile building block for cyclobutane-containing scaffolds in medicinal chemistry. The bromide functionality enables palladium-catalyzed cross-coupling reactions, while the tert-butyl carbamate group offers protection and stability under standard synthetic conditions. Its bench-stable nature and compatibility with diverse reaction environments facilitate efficient access to functionalized cyclobutanes in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   2.437
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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