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CS-W001157 4
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N-Methoxy-N-methylacrylamide

  • CAS No. 193634-77-4

  • Cat. No. CS-0128673
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Methoxy-N-methylacrylamide|CS-0128673

Structure of 193634-77-4

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General Information

  • CAS No. 193634-77-4
  • Cat. No. CS-0128673
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₂
  • Molecular Weight 115.13
  • Synonym(s) N-methoxy-N-methylprop-2-enamide
  • SMILES C=CC(N(OC)C)=O

Description

N-Methoxy-N-methylacrylamide is a bench-stable acrylamide derivative featuring a methoxy group that enhances reactivity in radical polymerization. This compound integrates readily into functional copolymers, offering improved solubility and controlled chain growth under standard conditions.

Application

N-Methoxy-N-methylacrylamide serves as a versatile Michael acceptor and enolizable electrophile in synthetic organic chemistry. It facilitates efficient C–C bond formation via conjugate addition, particularly in the construction of substituted pyrrolidines and other nitrogen-containing heterocycles. The molecule exhibits good bench stability, mild reaction conditions, and compatibility with diverse functional groups, enabling straightforward purification and scalability. Its reactivity profile makes it a reliable building block for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H312-H315-H318-H332-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   0.1922
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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