5-Chloro-2,3-dihydrofuro[2,3-c]pyridine

Name: 5-Chloro-2,3-dihydrofuro[2,3-c]pyridine
Brand: ChemScene
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CAS No. 193605-52-6
Cat. No. CS-0162793
Purity≥98%
MDL No.None

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FedEx Limited Quantities Ground	$0.00
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5-Chloro-2,3-dihydrofuro[2,3-c]pyridine|CS-0162793

Structure of 193605-52-6

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General Information

CAS No. 193605-52-6
Cat. No. CS-0162793
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClNO
Molecular Weight 155.58
Synonym(s) None
SMILES ClC1=CC2=C(OCC2)C=N1

Description

5-Chloro-2,3-dihydrofuro[2,3-c]pyridine is a heterocyclic scaffold featuring a fused furan-pyridine core with a chlorine substituent at the 5-position. This electron-deficient system integrates readily into medicinal chemistry libraries, offering enhanced metabolic stability and improved solubility profiles in synthetic pathways. The molecule's rigid, planar geometry supports precise molecular positioning in target binding interactions.

Application

5-Chloro-2,3-dihydrofuro[2,3-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. Its fused furan-pyridine core enables robust functionalization at multiple sites, with the chlorine substituent facilitating nucleophilic substitution or cross-coupling reactions. The compound exhibits good bench stability and compatibility with standard reaction conditions, making it suitable for modular synthesis of complex scaffolds in drug discovery workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

TPSA 22.12
LogP 1.6699
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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5-Chloro-2,3-dihydrofuro[2,3-c]pyridine

CAS No. 193605-52-6

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