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CS-W001157 4
Total: USD 88.00

2,5-Difluorophenylboronic acid

  • CAS No. 193353-34-3

  • Cat. No. CS-0007591
  • Purity≥97%
  • MDL No.MFCD01863171

*For research and further manufacturing use only, not for direct human use.

2,5-Difluorophenylboronic acid|CS-0007591

Structure of 193353-34-3

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General Information

  • CAS No. 193353-34-3
  • Cat. No. CS-0007591
  • Purity ≥97%
  • MDL No. MFCD01863171
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BF₂O₂
  • Molecular Weight 157.91
  • Synonym(s) None
  • SMILES FC1=CC=C(F)C(B(O)O)=C1

Description

2,5-Difluorophenylboronic acid features a boronic acid functional group flanked by two fluorine substituents at the 2 and 5 positions of the phenyl ring. This electron-deficient arylboronic acid enables efficient Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering high yields in the synthesis of biaryl scaffolds. The difluoro substitution enhances stability and modulates reactivity for selective transformations.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.3554
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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