Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Fluoro-4-formylbenzoic acid

  • CAS No. 193290-80-1

  • Cat. No. CS-0094284
  • Purity≥95%
  • MDL No.MFCD20483546

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-4-formylbenzoic acid|CS-0094284

Structure of 193290-80-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 193290-80-1
  • Cat. No. CS-0094284
  • Purity ≥95%
  • MDL No. MFCD20483546
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅FO₃
  • Molecular Weight 168.12
  • Synonym(s) Benzoic acid,3-fluoro-4-formyl
  • SMILES O=C(O)C1=CC=C(C=O)C(F)=C1

Description

3-Fluoro-4-formylbenzoic acid features a formyl group adjacent to a carboxylic acid, enabling direct coupling reactions. The ortho-fluorine enhances electrophilicity and facilitates downstream functionalization. This electron-deficient aromatic scaffold integrates readily into pharmaceutical intermediates and bioactive molecule frameworks under standard conditions.

Application

3-Fluoro-4-formylbenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The ortho-fluoro and para-formyl groups enable selective functionalization via nucleophilic substitution or condensation reactions, while the carboxylic acid facilitates derivatization through esterification, amide coupling, or salt formation. Its bench-stable crystalline form and compatibility with standard reaction conditions make it well-suited for scalable medicinal chemistry campaigns.

Synthesis

  • Route1

    References

    • SCHERING CORPORATION Patent: WO2008/130584 A1, 2008 ; Location in patent: Page/Page column 144 ; WO 2008/130584 A1
  • Route2

    References

    • JERINI AG Patent: WO2009/36996 A2, 2009 ; Location in patent: Page/Page column 88 ; WO 2009/036996 A2
  • Route3

    References

    • Almirall, S.A. Patent: EP2526945 A1, 2012 ; EP 2526945 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   54.37
  • LogP   1.3364
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Fluoro-4-formylbenzoic acid sigma3-Fluoro-4-formylbenzoic acid manufacturer3-Fluoro-4-formylbenzoic acid price3-Fluoro-4-formylbenzoic acid structure3-Fluoro-4-formylbenzoic acid SDSbuy 3-Fluoro-4-formylbenzoic acid3-Fluoro-4-formylbenzoic acid supplier3-Fluoro-4-formylbenzoic acid uses3-Fluoro-4-formylbenzoic acid molecular weightprice of 3-Fluoro-4-formylbenzoic acid3-Fluoro-4-formylbenzoic acid chemical name formula of 3-Fluoro-4-formylbenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label