Lot numbers can be found on the outside label of a product:
3-Fluoro-4-formylbenzonitrile
-
CAS No. 105942-10-7
- Cat. No. CS-W004827
- Purity≥96%
- MDL No.MFCD07368786
*For research and further manufacturing use only, not for direct human use.
Structure of 105942-10-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 105942-10-7
- Cat. No. CS-W004827
- Purity ≥96%
- MDL No. MFCD07368786
- Storage 4°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₄FNO
- Molecular Weight 149.12
- Synonym(s) 4-Cyano-2-fluorobenzaldehyde
- SMILES C(#N)C1=CC(=C(C=O)C=C1)F
Description
3-Fluoro-4-formylbenzonitrile features a fluorinated aromatic core with complementary formyl and nitrile groups positioned for orthogonal reactivity. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key building block in pharmaceutical synthesis, where its solubility and stability under standard conditions support efficient derivatization workflows.
Application
3-Fluoro-4-formylbenzonitrile serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted heterocycles via nucleophilic addition and condensation reactions. The ortho-fluoro and formyl groups facilitate directed metalation and regioselective functionalization, while the nitrile group supports hydrolysis or cycloaddition pathways. Its bench-stable nature and compatibility with common reaction conditions make it well-suited for iterative synthesis workflows in medicinal chemistry.
Synthesis
-
Route1
-
In-stock
133059-44-6 -
97674-02-7 - ~87%
-
In-stock
105942-10-7
References
-
JANSSEN PHARMACEUTICA NV; MEERPOEL, Lieven; MAES, Louis, Jules, Roger, Marie; DE WIT, Kelly Patent: WO2011/154298 A1, 2011 ; Location in patent: Page/Page column 36-37 ; WO 2011/154298 A1
-
-
Route2
-
In-stock
170572-49-3 - ~20%
-
In-stock
105942-10-7
References
-
BAYER PHARMA AKTIENGESELLSCHAFT Patent: US2012/94968 A1, 2012 ; Location in patent: Page/Page column 26 ;
-
-
Route3
-
In-stock
219873-06-0 - ~94%
-
In-stock
105942-10-7
References
-
MILLENNIUM PHARMACEUTICALS, INC. Patent: WO2006/2099 A2, 2006 ; Location in patent: Page/Page column 104 ; WO 2006/002099 A2
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 40.86
- LogP 1.50988
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 3-Fluoro-4-formylbenzonitrile sigma3-Fluoro-4-formylbenzonitrile manufacturer3-Fluoro-4-formylbenzonitrile price3-Fluoro-4-formylbenzonitrile structure3-Fluoro-4-formylbenzonitrile SDSbuy 3-Fluoro-4-formylbenzonitrile3-Fluoro-4-formylbenzonitrile supplier3-Fluoro-4-formylbenzonitrile uses3-Fluoro-4-formylbenzonitrile molecular weightprice of 3-Fluoro-4-formylbenzonitrile3-Fluoro-4-formylbenzonitrile chemical name formula of 3-Fluoro-4-formylbenzonitrile