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CS-W001157 4
Total: USD 88.00

1,1-Diethoxy-3-phenylpropan-2-one

  • CAS No. 19256-31-6

  • Cat. No. CS-0043260
  • Purity≥95%
  • MDL No.MFCD11555168

*For research and further manufacturing use only, not for direct human use.

1,1-Diethoxy-3-phenylpropan-2-one|CS-0043260

Structure of 19256-31-6

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General Information

  • CAS No. 19256-31-6
  • Cat. No. CS-0043260
  • Purity ≥95%
  • MDL No. MFCD11555168
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈O₃
  • Molecular Weight 222.28
  • Synonym(s) 2-Propanone, 1,1-diethoxy-3-phenyl-
  • SMILES O=C(CC1=CC=CC=C1)C(OCC)OCC

Description

This α,β-unsaturated ketone features a phenyl group at the β-position and two ethoxy substituents on the α-carbon, enhancing solubility and stability. The conjugated system enables efficient participation in Michael additions and Claisen-type condensations under mild conditions.

Application

1,1-Diethoxy-3-phenylpropan-2-one serves as a stable, bench-ready synthon for the construction of β-keto ester analogs and functionalized ketones. It facilitates efficient Michael additions and Claisen-type condensations, enabling access to complex carbonyl architectures with high regiocontrol. The molecule exhibits excellent functional group tolerance and simplifies purification due to its crystalline nature and predictable reactivity profile in standard organic transformations.

Synthesis

  • Route1
    • null|null
      6921-34-2
    • In-stock
      Ethyl diethoxyacetate|CS-W001603
      6065-82-3
    • ~96%
    • In-stock
      1,1-Diethoxy-3-phenylpropan-2-one|CS-0043260
      19256-31-6

    References

    • Adamczyk, Maciej; Johnson, Donald D.; Mattingly, Phillip G.; Pan, You; Reddy, Rajarathnam E. Synthetic Communications, 2002 , vol. 32, # 20 p. 3199 - 3205
  • Route2
    • null|null
      20461-78-3
    • ~%
    • In-stock
      1,1-Diethoxy-3-phenylpropan-2-one|CS-0043260
      19256-31-6

    References

    • Dahn,H. et al. Helvetica Chimica Acta, 1963 , vol. 46, p. 1000 - 1006
  • Route3
    • null|null
      1638-63-7
    • ~%
    • In-stock
      1,1-Diethoxy-3-phenylpropan-2-one|CS-0043260
      19256-31-6

    References

    • Dahn,H. et al. Helvetica Chimica Acta, 1963 , vol. 46, p. 1000 - 1006

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   2.1973
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   7

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