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CS-W001157 4
Total: USD 88.00

2,2,6,6-Tetramethylmorpholine

  • CAS No. 19151-69-0

  • Cat. No. CS-0147917
  • Purity≥98%
  • MDL No.MFCD09897730

*For research and further manufacturing use only, not for direct human use.

2,2,6,6-Tetramethylmorpholine|CS-0147917

Structure of 19151-69-0

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General Information

  • CAS No. 19151-69-0
  • Cat. No. CS-0147917
  • Purity ≥98%
  • MDL No. MFCD09897730
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO
  • Molecular Weight 143.23
  • Synonym(s) None
  • SMILES CC1(C)OC(C)(C)CNC1

Description

2,2,6,6-Tetramethylmorpholine is a sterically hindered amine featuring a saturated six-membered ring with four methyl groups strategically positioned at the 2 and 6 carbons. This configuration imparts high steric bulk and enhanced basicity while maintaining excellent solubility in organic solvents. The molecule exhibits robust bench stability and functions effectively as a non-nucleophilic base in catalytic reactions. Its rigid structure facilitates precise stereochemical control in synthetic transformations.

Application

2,2,6,6-Tetramethylmorpholine serves as a sterically hindered amine base in synthetic organic chemistry, enabling efficient deprotonation and neutralization reactions under mild conditions. Its robust stability and low nucleophilicity make it ideal for selective transformations, particularly in coupling reactions and catalytic processes where minimal side reactivity is required. The compound functions effectively in both laboratory-scale syntheses and scalable industrial applications, offering reliable performance with easy handling and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.1634
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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