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CS-W001157 4
Total: USD 88.00

2,2-Dimethylmorpholine hydrochloride

  • CAS No. 167946-94-3

  • Cat. No. CS-0052185
  • Molecule weight151.63
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,2-Dimethylmorpholine hydrochloride|CS-0052185

Structure of 167946-94-3

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General Information

  • CAS No. 167946-94-3
  • Cat. No. CS-0052185
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClNO
  • Molecular Weight 151.63
  • Synonym(s) 2,2-dimethylmorpholine,hydrochloride
  • SMILES Cl.CC1(C)CNCCO1

Description

2,2-Dimethylmorpholine hydrochloride is a bench-stable, moisture-tolerant heterocyclic salt featuring a tertiary amine center. This form enhances solubility in aqueous media while maintaining thermal stability during standard synthetic workflows. The dimethyl substitution reduces basicity slightly compared to morpholine, enabling selective reactivity in nucleophilic transformations and facilitating purification via ion-exchange chromatography.

Application

2,2-Dimethylmorpholine hydrochloride serves as a stable, bench-ready source of the 2,2-dimethylmorpholine moiety, enabling efficient nucleophilic substitution and reductive amination protocols. Its tertiary amine functionality offers enhanced solubility in polar solvents and improved stability under standard reaction conditions. The salt form facilitates handling and purification, making it a practical building block for heterocyclic synthesis and medicinal chemistry applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.8066
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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