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tert-Butyl (S)-2-((methylamino)methyl)pyrrolidine-1-carboxylate

  • CAS No. 191231-58-0

  • Cat. No. CS-0135254
  • Purity≥95%
  • MDL No.MFCD07786221

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (S)-2-((methylamino)methyl)pyrrolidine-1-carboxylate|CS-0135254

Structure of 191231-58-0

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General Information

  • CAS No. 191231-58-0
  • Cat. No. CS-0135254
  • Purity ≥95%
  • MDL No. MFCD07786221
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂N₂O₂
  • Molecular Weight 214.30
  • Synonym(s) (S)-Tert-butyl 2-((methylamino)methyl)pyrrolidine-1-carboxylate
  • SMILES O=C(N1[C@H](CNC)CCC1)OC(C)(C)C

Description

This chiral pyrrolidine derivative features a tert-butyl ester group and a methylamino-methyl substituent on the (S)-pyrrolidine ring, enabling efficient incorporation into peptidomimetics. The protected amine and sterically hindered backbone offer enhanced stability and selectivity in synthetic applications.

Application

tert-Butyl (S)-2-((methylamino)methyl)pyrrolidine-1-carboxylate serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive pyrrolidine-containing scaffolds. The protected amine and functionalized pyrrolidine core offer excellent stability, ease of purification, and compatibility with standard coupling reactions, facilitating downstream transformations in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.6053
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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