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Structure of 190851-19-5
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Tert-butyl N-(4-amino-2-methoxyphenyl)carbamate features a protected aniline scaffold with a methoxy group at the ortho position, enhancing solubility and stability. This bench-stable derivative enables direct incorporation into peptide coupling sequences and serves as a key intermediate in the synthesis of bioactive arylamines.
Tert-butyl N-(4-amino-2-methoxyphenyl)carbamate serves as a versatile protected amine intermediate in medicinal chemistry synthesis. The tert-butyl carbamate group provides excellent bench stability and orthogonal deprotection under mild acidic conditions. The 4-amino-2-methoxyphenyl moiety enables direct coupling reactions for constructing biologically relevant scaffolds, including kinase inhibitors and CNS-targeted compounds. Functional group tolerance supports subsequent derivatization via amide formation, Suzuki coupling, or electrophilic substitution, making it a practical building block for lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: