Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromo-3-methoxyaniline

  • CAS No. 19056-40-7

  • Cat. No. CS-W007360
  • Purity≥97%
  • MDL No.MFCD05664063

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-methoxyaniline|CS-W007360

Structure of 19056-40-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 19056-40-7
  • Cat. No. CS-W007360
  • Purity ≥97%
  • MDL No. MFCD05664063
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrNO
  • Molecular Weight 202.05
  • Synonym(s) 4-Bromo-m-anisidine
  • SMILES BrC1=C(C=C(N)C=C1)OC

Description

4-Bromo-3-methoxyaniline features a bromine substituent at the para position relative to the amino group and a methoxy group ortho to the amine, creating a uniquely functionalized aryl scaffold. This electron-rich aniline derivative enables direct coupling in palladium-catalyzed cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive heterocycles and pharmaceuticals.

Application

4-Bromo-3-methoxyaniline serves as a versatile building block in medicinal chemistry and materials science, enabling direct incorporation into heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its bromo group facilitates Suzuki, Stille, and Buchwald–Hartwig couplings, while the methoxy and aniline functionalities offer orthogonal reactivity for downstream derivatization. The compound exhibits good bench stability and is readily purified by column chromatography, making it well-suited for scalable synthesis of functionalized arylamines.

Synthesis

  • Route1

    References

    • Norwich Eaton Pharmaceuticals, Inc. Patent: US4882354 A1, 1989 ;
  • Route2

    References

    • Chretien, Jean-Mathieu; Zammattio, Francoise; Le Grognec, Erwan; Paris, Michael; Cahingt, Blanche; Montavon, Gilles; Quintard, Jean-Paul Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2870 - 2873
  • Route3
    • In-stock
      1-Bromo-2-methoxybenzene|CS-W007633
      578-57-4
    • null|null
      7439-89-6
    • ~%
    • In-stock
      4-Bromo-3-methoxyaniline|CS-W007360
      19056-40-7

    References

    • US2003/158179 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.0399
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Bromo-3-methoxyaniline sigma4-Bromo-3-methoxyaniline manufacturer4-Bromo-3-methoxyaniline price4-Bromo-3-methoxyaniline structure4-Bromo-3-methoxyaniline SDSbuy 4-Bromo-3-methoxyaniline4-Bromo-3-methoxyaniline supplier4-Bromo-3-methoxyaniline uses4-Bromo-3-methoxyaniline molecular weightprice of 4-Bromo-3-methoxyaniline4-Bromo-3-methoxyaniline chemical name formula of 4-Bromo-3-methoxyaniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label