Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-(Trifluoromethyl)quinazolin-2-amine

  • CAS No. 190273-94-0

  • Cat. No. CS-0042131
  • Molecule weight213.16
  • Purity≥97%
  • MDL No.MFCD00835296

*For research and further manufacturing use only, not for direct human use.

6-(Trifluoromethyl)quinazolin-2-amine|CS-0042131

Structure of 190273-94-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 190273-94-0
  • Cat. No. CS-0042131
  • Purity ≥97%
  • MDL No. MFCD00835296
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆F₃N₃
  • Molecular Weight 213.16
  • Synonym(s) 6-(trifluoromethyl)-2-quinazolinamine
  • SMILES NC1=NC=C2C=C(C(F)(F)F)C=CC2=N1

Description

6-(Trifluoromethyl)quinazolin-2-amine integrates a trifluoromethyl group at the 6-position of the quinazoline scaffold, enhancing electron-withdrawing character and metabolic stability. This moiety enables direct incorporation into kinase inhibitor scaffolds, offering improved membrane permeability and target engagement in medicinal chemistry campaigns.

Application

6-(Trifluoromethyl)quinazolin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to kinase-inhibitor scaffolds. Its trifluoromethyl group enhances metabolic stability and membrane permeability, while the quinazoline core facilitates robust coupling reactions. The amine functionality supports direct derivatization and salt formation, offering improved solubility and handling—ideal for high-throughput synthesis and lead optimization workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   2.2308
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-(Trifluoromethyl)quinazolin-2-amine sigma6-(Trifluoromethyl)quinazolin-2-amine manufacturer6-(Trifluoromethyl)quinazolin-2-amine price6-(Trifluoromethyl)quinazolin-2-amine structure6-(Trifluoromethyl)quinazolin-2-amine SDSbuy 6-(Trifluoromethyl)quinazolin-2-amine6-(Trifluoromethyl)quinazolin-2-amine supplier6-(Trifluoromethyl)quinazolin-2-amine uses6-(Trifluoromethyl)quinazolin-2-amine molecular weightprice of 6-(Trifluoromethyl)quinazolin-2-amine6-(Trifluoromethyl)quinazolin-2-amine chemical name formula of 6-(Trifluoromethyl)quinazolin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label