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Structure of 1896262-04-6
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This bench-stable boronate moiety integrates a fluorinated dihydrobenzofuran scaffold, offering enhanced metabolic stability and favorable solubility. The para-fluoro substitution modulates electronic properties, while the primary amine enables direct coupling in cross-coupling reactions and conjugation workflows.
(5-Fluoro-2,3-dihydrobenzofuran-4-yl)methanamine serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated heterocyclic scaffolds. Its pendant primary amine facilitates straightforward derivatization via amidation, alkylation, and reductive amination. The molecule exhibits good bench stability and functional group tolerance, supporting efficient incorporation into diverse API candidates and enabling rapid SAR exploration in target-directed campaigns.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: