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Structure of 18952-87-9
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1-Isopropylpyrazole is a bench-stable, nitrogen-rich heterocycle featuring a pyrazole core substituted with an isopropyl group at the 1-position. This configuration imparts enhanced solubility in organic solvents and facilitates incorporation into pharmaceutical scaffolds. The molecule serves as a key building block for bioactive compounds, particularly in medicinal chemistry applications where modulating metabolic stability and lipophilicity is critical.
1-Isopropylpyrazole serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-based scaffolds prevalent in bioactive molecules. Its isopropyl group enhances lipophilicity and metabolic stability, while the pyrazole core offers hydrogen-bonding capacity and planar rigidity. The compound exhibits good bench stability and functional group tolerance, facilitating straightforward derivatization via electrophilic substitution or transition-metal-catalyzed coupling reactions. It functions effectively in the synthesis of heterocyclic APIs and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P362-P370+P378-P501
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Lot numbers can be found on the outside label of a product: