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CS-W001157 4
Total: USD 88.00

3-Amino-2-piperidinone

  • CAS No. 1892-22-4

  • Cat. No. CS-D0182
  • Purity≥96%
  • MDL No.MFCD06809610

*For research and further manufacturing use only, not for direct human use.

3-Amino-2-piperidinone|CS-D0182

Structure of 1892-22-4

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General Information

  • CAS No. 1892-22-4
  • Cat. No. CS-D0182
  • Purity ≥96%
  • MDL No. MFCD06809610
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀N₂O
  • Molecular Weight 114.15
  • Synonym(s) Cyclo-ornithine
  • SMILES O=C1NCCCC1N

Description

3-Amino-2-piperidinone features a fused amine and carbonyl functionality within a saturated piperidinone ring, enabling direct incorporation into bioactive scaffolds. This bench-stable heterocycle serves as a key building block for medicinal chemistry campaigns targeting CNS therapeutics and kinase inhibitors.

Synthesis

  • Route1

    References

    • Journal of Heterocyclic Chemistry, , vol. 20, # 5 p. 1329 - 1334
  • Route2

    References

    • WO2005/75439 A1, ; Page/Page column 129 ; WO 2005/075439 A1
  • Route3
    • Methyl 2,5-diaminopentanoate hydrochloride|CS-0661137
      261522-14-9
    • ~%
    • In-stock
      3-Amino-2-piperidinone|CS-D0182
      1892-22-4

    References

    • WO2004/98589 A1, ; Page 163 ; WO 2004/098589 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   -0.7763
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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