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Structure of 189116-36-7
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5-Chloro-2-methylpyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with electron-withdrawing chlorine and methyl substituents, enabling robust integration into kinase inhibitor scaffolds. This bench-stable, moisture-tolerant compound pairs efficiently with palladium-catalyzed cross-coupling reactions, delivering high-yield access to diverse pharmacophores in medicinal chemistry workflows.
5-Chloro-2-methylpyrazolo[1,5-a]pyrimidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. Its chlorine atom at C5 provides a reliable site for nucleophilic substitution, while the methyl group enhances metabolic stability and modulates electronic properties. The scaffold exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in diverse reaction environments relevant to API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: