Lot numbers can be found on the outside label of a product:
N-Boc-hexahydro-1H-azepine-4-one
-
CAS No. 188975-88-4
- Cat. No. CS-D0285
- Purity≥97%
- MDL No.MFCD03788435
*For research and further manufacturing use only, not for direct human use.
Structure of 188975-88-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 188975-88-4
- Cat. No. CS-D0285
- Purity ≥97%
- MDL No. MFCD03788435
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₉NO₃
- Molecular Weight 213.27
- Synonym(s) None
- SMILES O=C1CCN(C(OC(C)(C)C)=O)CCC1
Description
N-Boc-hexahydro-1H-azepine-4-one features a stable, bench-ready Boc-protected lactam core with enhanced solubility in common organic solvents. This cyclic amide integrates readily into diverse synthetic routes, serving as a key scaffold for medicinal chemistry campaigns targeting nitrogen-rich heterocycles.
Application
N-Boc-hexahydro-1H-azepine-4-one serves as a versatile scaffold for the construction of nitrogen-containing heterocycles and bioactive molecules. The Boc-protected amine enables straightforward deprotection and functionalization, while the ketone at C4 facilitates selective reduction, enolization, or nucleophilic addition. This stable, bench-ready building block exhibits excellent functional group tolerance and is compatible with standard coupling and cyclization protocols in medicinal chemistry and process synthesis.
Synthesis
-
Route1
-
In-stock
141642-82-2 - ~99%
-
In-stock
188975-88-4
References
-
MORPHOCHEM AKTIENGESELLSCHAFT FUeR KOMBINATORISCHE CHEMIE Patent: WO2004/35569 A2, 2004 ; Location in patent: Page/Page column 58 ;
-
-
References
-
JANSSEN RandD IRELAND; GUILLEMONT, Jerôme Emile Georges; LANÇOIS, David Francis Alain; MOTTE, Magali Madeleine Simone; BALEMANS, Wendy Mia Albert; KOUL, Anil Patent: WO2014/23815 A1, 2014 ; Location in patent: Page/Page column 37 ;
-
-
Route3
-
In-stock
478832-21-2 - ~83%
-
In-stock
188975-88-4
References
-
Sumitomo Pharmaceuticals Company, Limited Patent: EP1500643 A1, 2005 ; Location in patent: Page 48 ; EP 1500643 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 46.61
- LogP 1.9765
- H_Acceptors 3
- H_Donors H_Donors：
- Rotatable_Bonds Rotatable_Bonds：
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- N-Boc-hexahydro-1H-azepine-4-one sigmaN-Boc-hexahydro-1H-azepine-4-one manufacturerN-Boc-hexahydro-1H-azepine-4-one priceN-Boc-hexahydro-1H-azepine-4-one structureN-Boc-hexahydro-1H-azepine-4-one SDSbuy N-Boc-hexahydro-1H-azepine-4-oneN-Boc-hexahydro-1H-azepine-4-one supplierN-Boc-hexahydro-1H-azepine-4-one usesN-Boc-hexahydro-1H-azepine-4-one molecular weightprice of N-Boc-hexahydro-1H-azepine-4-oneN-Boc-hexahydro-1H-azepine-4-one chemical name formula of N-Boc-hexahydro-1H-azepine-4-one