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CS-W001157 4
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(6-Bromopyridin-2-yl)methanamine

  • CAS No. 188637-63-0

  • Cat. No. CS-W019867
  • Purity≥95%
  • MDL No.MFCD07367930
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(6-Bromopyridin-2-yl)methanamine|CS-W019867

Structure of 188637-63-0

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Description

This bench-stable boronate moiety integrates readily into Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The para-nitro group enhances electrophilicity, while the amine functionality facilitates downstream derivatization in medicinal chemistry applications.

Application

(6-Bromopyridin-2-yl)methanamine serves as a versatile building block for constructing pyridine-based pharmaceutical intermediates and functional materials. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the primary amine functions as a site for derivatization via acylation, alkylation, or reductive amination. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

General Information

  • CAS No. 188637-63-0
  • Cat. No. CS-W019867
  • Purity ≥95%
  • MDL No. MFCD07367930
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) 1-(6-bromopyridin-2-yl)methanamine
  • SMILES NCC1=NC(Br)=CC=C1

Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.3028
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group :
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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