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CS-W001157 4
Total: USD 88.00

(Rac)-Rasagiline

  • CAS No. 1875-50-9

  • Cat. No. CS-0064076
  • Molecule weight171.24
  • Purity≥97%
  • MDL No.MFCD00033000

*For research and further manufacturing use only, not for direct human use.

(Rac)-Rasagiline|CS-0064076

Structure of 1875-50-9

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General Information

  • CAS No. 1875-50-9
  • Cat. No. CS-0064076
  • Purity ≥97%
  • MDL No. MFCD00033000
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃N
  • Molecular Weight 171.24
  • Synonym(s) AGN1135; (Rac)-TVP1012
  • SMILES C#CCNC1CCC2=C1C=CC=C2

Description

(Rac)-Rasagiline is a potent, irreversible monoamine oxidase B (MAO-B) inhibitor featuring a stable, chiral scaffold with enhanced metabolic resilience. This compound integrates seamlessly into neuroprotective research workflows, offering consistent activity under standard bench conditions.

Application

(Rac)-Rasagiline serves as a well-established irreversible monoamine oxidase-B (MAO-B) inhibitor, widely utilized in the clinical management of Parkinson’s disease. Its structural stability and selective enzyme inhibition profile enable consistent neuroprotective effects with minimal off-target interactions. The racemic form offers reliable synthetic accessibility and reproducible pharmacological activity, making it a practical reference compound in medicinal chemistry and CNS drug development workflows.

Synthesis

  • Route1
    • null|null
      1227784-59-9
    • ~%
    • In-stock
      (Rac)-Rasagiline|CS-0064076
      1875-50-9

    References

    • WO2010/59913 A2, ; Page/Page column 16-17 ;
  • Route2
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • null|null
      2450-71-7
    • ~89%
    • In-stock
      (Rac)-Rasagiline|CS-0064076
      1875-50-9

    References

    • DIPHARMA FRANCIS S.r.I. Patent: US2010/29987 A1, 2010 ; Location in patent: Page/Page column 3-4 ;
  • Route3
    • In-stock
      Prop-2-yn-1-yl benzenesulfonate|CS-W010595
      6165-75-9
    • 2,3-Dihydro-1H-inden-1-amine Rasagiline  Impurity|CS-0229097
      34698-41-4
    • ~99%
    • In-stock
      (Rac)-Rasagiline|CS-0064076
      1875-50-9

    References

    • Frenkel, Anton; Lidor-Hadas, Ramy; Bahar, Eliezer Patent: US2011/152381 A1, 2011 ; Location in patent: Page/Page column 8-9 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.8967
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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