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CS-W001157 4
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Methyl tetrahydro-2H-pyran-3-carboxylate

  • CAS No. 18729-20-9

  • Cat. No. CS-W001863
  • Purity≥95%
  • MDL No.MFCD09839011

*For research and further manufacturing use only, not for direct human use.

Methyl tetrahydro-2H-pyran-3-carboxylate|CS-W001863

Structure of 18729-20-9

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General Information

  • CAS No. 18729-20-9
  • Cat. No. CS-W001863
  • Purity ≥95%
  • MDL No. MFCD09839011
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₃
  • Molecular Weight 144.17
  • Synonym(s) methyl tetrahydropyran-3-carboxylate
  • SMILES COC(=O)C1CCCOC1

Description

Methyl tetrahydro-2H-pyran-3-carboxylate features a stereogenic center within a stable, moisture-tolerant tetrahydropyran ring, enabling reliable incorporation into complex syntheses. The ester functionality delivers predictable reactivity under standard conditions, supporting efficient transformations in natural product and pharmaceutical development workflows.

Application

Methyl tetrahydro-2H-pyran-3-carboxylate serves as a versatile building block in synthetic organic chemistry, offering a stable, bench-ready platform for stereoselective transformations. Its tetrahydropyran ring provides conformational rigidity and orthogonality to common protecting groups, while the ester functionality enables facile derivatization via hydrolysis, reduction, or cross-coupling. This compound facilitates efficient access to complex heterocyclic scaffolds and bioactive molecule intermediates through well-established reaction pathways.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   0.586
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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