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CS-W001157 4
Total: USD 88.00

1-(Pyridin-2-yl)ethanol

  • CAS No. 18728-61-5

  • Cat. No. CS-W003280
  • Purity≥98%
  • MDL No.MFCD06245419

*For research and further manufacturing use only, not for direct human use.

1-(Pyridin-2-yl)ethanol|CS-W003280

Structure of 18728-61-5

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General Information

  • CAS No. 18728-61-5
  • Cat. No. CS-W003280
  • Purity ≥98%
  • MDL No. MFCD06245419
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.15
  • Synonym(s) 1-PYRIDIN-2-YL-ETHANOL
  • SMILES CC(c1ccccn1)O

Description

1-(Pyridin-2-yl)ethanol features a pyridine ring directly linked to a hydroxyethyl side chain, combining aromatic stability with a reactive primary alcohol. This configuration enables seamless integration into synthetic routes requiring polar, heterocyclic scaffolds. The molecule exhibits favorable solubility in common organic solvents and maintains stability under standard bench conditions, facilitating use in pharmaceutical intermediates and ligand design.

Application

1-(Pyridin-2-yl)ethanol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functional group transformations. Its pyridyl moiety provides enhanced solubility and metabolic stability, while the secondary alcohol facilitates efficient derivatization via esterification, etherification, or oxidation to ketones. Bench-stable and readily purified by distillation or chromatography, it functions reliably in coupling reactions and multistep syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.1349
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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