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Structure of 187035-79-6
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Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability. The chloro substituent enables selective nucleophilic substitution, while the ester functionality supports further derivatization. This bench-stable building block integrates efficiently into pharmaceutical scaffolds requiring heterocyclic core diversity.
Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of pyrimidine-based scaffolds. The chloro group at C2 facilitates nucleophilic substitution, while the trifluoromethyl and ester functionalities offer enhanced metabolic stability and synthetic handle for further derivatization. Its bench-stable nature and compatibility with standard coupling reactions make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: