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Structure of 1868-00-4
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Bis(3-(trifluoromethyl)phenyl)methanone features two electron-deficient aryl rings flanking a ketone group, enabling robust participation in cross-coupling and electrophilic aromatic substitution reactions. The trifluoromethyl substituents enhance stability and modulate reactivity, making this compound valuable in synthetic organic chemistry and pharmaceutical intermediate development.
Bis(3-(trifluoromethyl)phenyl)methanone serves as a robust diaryl ketone building block in synthetic organic chemistry, enabling efficient construction of complex aromatic scaffolds. Its trifluoromethyl substituents enhance metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The molecule exhibits good bench stability and facilitates electrophilic functionalization, nucleophilic addition, and transition-metal-catalyzed coupling reactions. Widely used in the synthesis of heterocyclic intermediates and API precursors, it functions reliably in standard laboratory workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: