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Structure of 728-81-4
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Phenyl(3-(trifluoromethyl)phenyl)methanone features a sterically hindered aryl ketone core with strong electron-withdrawing trifluoromethyl substitution. This configuration enhances stability and facilitates directed functionalization in synthetic transformations. The molecule integrates readily into complex scaffolds requiring high chemical robustness under standard conditions.
Phenyl(3-(trifluoromethyl)phenyl)methanone serves as a versatile aryl ketone building block for the synthesis of biaryl systems and heterocyclic scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carbonyl functionality enables reliable nucleophilic addition and condensation reactions. The compound exhibits excellent bench stability and is compatible with standard purification protocols, facilitating its use in medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: