2,4-Dimethoxypyridine

Name: 2,4-Dimethoxypyridine
Brand: ChemScene
Availability: InStock
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CAS No. 18677-43-5
Cat. No. CS-W018921
Purity≥98%
MDL No.MFCD01646187

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 18677-43-5

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Description

2,4-Dimethoxypyridine features two methoxy groups at the 2- and 4-positions of the pyridine ring, enhancing electron density and directing electrophilic substitution. This bench-stable, moisture-tolerant heterocycle integrates readily into cross-coupling reactions and serves as a key scaffold in medicinal chemistry and agrochemical synthesis.

Application

2,4-Dimethoxypyridine serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds. Its ortho-dialkoxy substitution pattern enhances electrophilic aromatic substitution reactivity while providing stable, bench-ready functionality for subsequent transformations. The molecule functions effectively in cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive compounds and pharmaceutical candidates.

General Information

CAS No. 18677-43-5
Cat. No. CS-W018921
Purity ≥98%
MDL No. MFCD01646187
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₉NO₂
Molecular Weight 139.15
Synonym(s) 2-heptenal, (2E)-
SMILES COC1=CC(OC)=NC=C1

Computational Chemistry Data

TPSA 31.35
LogP 1.0988
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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2,4-Dimethoxypyridine

CAS No. 18677-43-5

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