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CS-W001157 4
Total: USD 88.00

tert-Butyl (2-hydroxyphenyl)carbamate

  • CAS No. 186663-74-1

  • Cat. No. CS-0031385
  • Purity≥97%
  • MDL No.MFCD06411300
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-hydroxyphenyl)carbamate|CS-0031385

Structure of 186663-74-1

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Description

tert-Butyl (2-hydroxyphenyl)carbamate delivers a protected hydroxyl group on a phenolic scaffold, enabling stable handling and selective deprotection under mild acidic conditions. This carbamate functionality integrates seamlessly into synthetic sequences requiring orthogonal protection strategies in complex molecule assembly.

Application

tert-Butyl (2-hydroxyphenyl)carbamate serves as a stable, bench-ready protecting group for ortho-hydroxyaniline derivatives. It enables selective protection of the amine in the presence of phenolic hydroxyls, facilitating downstream functionalization and heterocycle construction. The carbamate moiety is compatible with standard deprotection conditions (e.g., TFA), allowing straightforward access to free 2-aminophenol scaffolds used in pharmaceutical intermediates and agrochemical synthesis.

General Information

  • CAS No. 186663-74-1
  • Cat. No. CS-0031385
  • Purity ≥97%
  • MDL No. MFCD06411300
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅NO₃
  • Molecular Weight 209.24
  • Synonym(s) N-Boc-2-aminophenol
  • SMILES O=C(NC1=CC=CC=C1O)OC(C)(C)C

Computational Chemistry Data

  • TPSA   58.56
  • LogP   2.7392
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362-P501

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