Lot numbers can be found on the outside label of a product:
Methyl (S)-piperidine-2-carboxylate hydrochloride
-
CAS No. 18650-39-0
- Cat. No. CS-W001485
- Purity≥97%
- MDL No.MFCD00672366
*For research and further manufacturing use only, not for direct human use.
Structure of 18650-39-0
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 18650-39-0
- Cat. No. CS-W001485
- Purity ≥97%
- MDL No. MFCD00672366
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₁₄ClNO₂
- Molecular Weight 179.64
- Synonym(s) L-HOMOPRO-OME-HCL
- SMILES O=C(OC)[C@@H]1CCCCN1.Cl
Description
Methyl (S)-piperidine-2-carboxylate hydrochloride is a chiral building block featuring a stereodefined piperidine core with a methyl ester group. This bench-stable, moisture-tolerant salt facilitates efficient incorporation into peptide-like scaffolds and serves as a key intermediate in the synthesis of bioactive molecules requiring defined stereochemistry.
Application
Methyl (S)-piperidine-2-carboxylate hydrochloride serves as a chiral building block for synthesizing bioactive molecules, leveraging the piperidine scaffold prevalent in medicinal chemistry. Its well-defined stereochemistry and bench-stable hydrochloride salt facilitate handling and purification. The ester group enables selective transformations, including reduction to the primary amine or incorporation into peptide-like structures. This compound functions effectively in asymmetric synthesis and supports the construction of heterocyclic frameworks found in pharmaceutical intermediates.
Synthesis
-
Route1
-
67-56-1 -
In-stock
3105-95-1 - ~99%
-
In-stock
18650-39-0
References
-
Ganellin, C. Robin; Bishop, Paul B.; Bambal, Ramesh B.; Chan, Suzanne M. T.; Leblond, Bertrand; Moore, Andrew N. J.; Zhao, Lihua; Bourgeat, Pierre; Rose, Christiane; Vargas, Froylan; Schwartz, Jean-Charles Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7333 - 7342
-
-
Route2
-
4043-87-2
- ~%
-
In-stock
18650-39-0
References
-
US2003/176430 A1, ;
-
-
Route3
-
67-56-1
-
In-stock
26250-84-0 - ~10%
-
In-stock
18650-39-0
References
-
Lamb, Jeffrey P.; Engers, Darren W.; Niswender, Colleen M.; Rodriguez, Alice L.; Venable, Daryl F.; Conn, Jeffrey P.; Lindsley, Craig W. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 9 p. 2711 - 2714
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 38.33
- LogP 0.7233
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 18650-39-0 sigma18650-39-0 manufacturer18650-39-0 price18650-39-0 structure18650-39-0 SDSbuy 18650-39-018650-39-0 supplier18650-39-0 uses18650-39-0 molecular weightprice of 18650-39-018650-39-0 chemical name formula of 18650-39-0