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Structure of 186498-30-6
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This brominated aromatic acid features a sterically hindered dimethylpropanoate backbone, enabling stable incorporation into complex synthetic architectures. The para-bromophenyl group provides a reactive handle for cross-coupling transformations, while the carboxylic acid functionality facilitates direct derivatization or conjugation under standard conditions.
3-(4-Bromophenyl)-2,2-dimethylpropanoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient construction of biaryl scaffolds via palladium-catalyzed cross-coupling reactions. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the sterically hindered tert-butyl carboxylic acid moiety enhances metabolic stability and provides a robust handle for derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring high functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: