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CS-W001157 4
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5-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

  • CAS No. 1072009-08-5

  • Cat. No. CS-0050479
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole|CS-0050479

Structure of 1072009-08-5

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General Information

  • CAS No. 1072009-08-5
  • Cat. No. CS-0050479
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₇BFNO₂
  • Molecular Weight 261.10
  • Synonym(s) 5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
  • SMILES CC1(C)OB(OC1(C)C)C1=C(F)C=CC2=C1C=CN2

Synthesis

  • Route1
    • 5-Fluoro-4-iodo-1H-indole|CS-1222385
      955978-88-8
    • null|null
      25015-63-8
    • ~84%
    • In-stock
      5-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole|CS-0050479
      1072009-08-5

    References

    • F.HOFFMANN-LA ROCHE AG Patent: WO2008/152394 A1, 2008 ; Location in patent: Page/Page column 26; 38 ; WO 2008/152394 A1
  • Route2
    • 5-Fluoro-4-iodo-1H-indole|CS-1222385
      955978-88-8
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~%
    • In-stock
      5-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole|CS-0050479
      1072009-08-5

    References

    • PIRAMED LIMITED; THE INSTITUTE OF CANCER RESEARCH Patent: WO2008/125835 A1, 2008 ; Location in patent: Referential example 10 ; WO 2008/125835 A1
  • Route3
    • 5-Fluoro-4-iodo-1H-indole|CS-1222385
      955978-88-8
    • ~%
    • In-stock
      5-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole|CS-0050479
      1072009-08-5

    References

    • F.HOFFMANN-LA ROCHE AG Patent: WO2008/152387 A1, 2008 ; Location in patent: Page/Page column 33 ; WO 2008/152387 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.25
  • LogP   2.6062
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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