2-Amino-5-chloro-3-fluorophenol

Name: 2-Amino-5-chloro-3-fluorophenol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 186309-72-8
Cat. No. CS-0163593
Molecule weight161.56
Purity≥97%
MDL No.MFCD25978072

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-chloro-3-fluorophenol|CS-0163593

Structure of 186309-72-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 186309-72-8
Cat. No. CS-0163593
Purity ≥97%
MDL No. MFCD25978072
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅ClFNO
Molecular Weight 161.56
Synonym(s) None
SMILES OC1=CC(Cl)=CC(F)=C1N

Description

2-Amino-5-chloro-3-fluorophenol features a trifunctional aromatic core with complementary reactivity. The electron-rich amine group pairs with the ortho-fluoro substituent to enable selective coupling, while the chlorine atom provides a handle for palladium-catalyzed cross-coupling. This scaffold delivers high functional group tolerance and stability under standard bench conditions.

Application

2-Amino-5-chloro-3-fluorophenol serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its ortho-halogenated phenolic framework facilitates palladium-catalyzed cross-coupling reactions and electrophilic substitution, while the amino and hydroxyl groups offer orthogonal functionalization pathways. The compound exhibits good bench stability and is amenable to standard purification techniques, supporting scalable synthesis of pharmaceutical intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 46.25
LogP 1.7669
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Amino-5-chloro-3-fluorophenol sigma2-Amino-5-chloro-3-fluorophenol manufacturer2-Amino-5-chloro-3-fluorophenol price2-Amino-5-chloro-3-fluorophenol structure2-Amino-5-chloro-3-fluorophenol SDSbuy 2-Amino-5-chloro-3-fluorophenol2-Amino-5-chloro-3-fluorophenol supplier2-Amino-5-chloro-3-fluorophenol uses2-Amino-5-chloro-3-fluorophenol molecular weightprice of 2-Amino-5-chloro-3-fluorophenol2-Amino-5-chloro-3-fluorophenol chemical name formula of 2-Amino-5-chloro-3-fluorophenol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Amino-5-chloro-3-fluorophenol

CAS No. 186309-72-8

Recommended Products